Searchable abstracts of presentations at key conferences in endocrinology

ea0029oc5.2 | Obesity Basic | ICEECE2012

Production of galectin-1, -3, -9 and -12 in adipose tissue of lean and obese mice

Rhodes D. , Pini M. , Montero-Melendez T. , Cooper D. , Perretti M. , Fantuzzi G.

Introduction: Obesity is characterized by an expanded and chronically inflamed adipose tissue (AT). The galectin (Gal) family of proteins exerts a variety of activities, including regulation of inflammation and adipogenesis.Methods: We used RT-PCR, ELISA and flow cytometry to evaluate regulation of expression and production of 4 members of the Gal family – Gal1, Gal3, Gal9 and Gal12 – in visceral (VAT) and subcutaneous (SAT) adipose tissue of m...